|
|
cholesteryl-beta-D-glucoside + H2O <=> cholesterol + D-glucose
|
3.2.1.104
steryl-beta-glucosidase
3.2.1.62
glycosylceramidase
|
–
–
|
|
|
BRENDA:
BR22654;
BS447309
KEGG:
R01460
MetaCyc:
STERYL-BETA-GLUCOSIDASE-RXN
|
|
|
|
cholesterol + O2 + reduced_adrenodoxin + H+ <=> pregnenolone + 4-Methylpentanal + H2O + oxidized_ferredoxin
|
1.14.15.6
cholesterol monooxygenase (side-chain-cleaving)
|
–
|
B
|
|
BRENDA:
BR29153;
BS386399
KEGG:
R02724
MetaCyc:
1.14.15.6-RXN
SABIO-RK:
2614
|
|
|
|
O2 + cholesterol <=> 5-Cholesten-3-one + H2O2
|
1.1.3.6
cholesterol oxidase
|
–
|
M
|
|
BRENDA:
BR29364
MetaCyc:
RXN-12778
|
|
|
|
cholesterol + NADP+ <=> 7-dehydrocholesterol + NADPH + H+
|
1.3.1.21
7-dehydrocholesterol reductase
|
–
|
BMK
|
|
BRENDA:
BR33764
KEGG:
R01456
MetaCyc:
RXN66-323
SABIO-RK:
1634
|
|
|
|
cholesterol + reduced_acceptor + O2 <=> 25-hydroxycholesterol + acceptor + H2O
|
1.14.99.38
cholesterol 25-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48560;
BS375089
KEGG:
R07218
MetaCyc:
1.14.99.38-RXN
|
|
|
|
cholesterol + O2 + reduced_adrenodoxin + H+ <=> (22R)-22-hydroxycholesterol + H2O + oxidized_ferredoxin
|
1.14.15.6
cholesterol monooxygenase (side-chain-cleaving)
|
–
|
MK
|
|
BRENDA:
BR50360
KEGG:
R02723
MetaCyc:
RXN-7875
|
|
|
|
cholesterol + O2 + NADPH + H+ <=> 7-dehydrocholesterol + NADP+ + H2O
|
1.14.19.21
cholesterol 7-desaturase
|
–
|
BMK
|
|
BRENDA:
BR51371
KEGG:
R11008
MetaCyc:
RXN-16379
|
|
|
|
cholesterol + O2 + NADH + H+ <=> 7-dehydrocholesterol + NAD+ + H2O
|
1.14.19.21
cholesterol 7-desaturase
|
–
|
K
|
|
BRENDA:
BR51371-a
KEGG:
R11007
MetaCyc:
RXN-16379_WOP
|
|
|
|
O2 + cholesterol <=> cholest-4-en-3-one + H2O2
|
1.1.3.6
cholesterol oxidase
|
–
|
K
|
|
BRENDA:
BS188843
KEGG:
R01459
MetaCyc:
CHOLESTEROL-OXIDASE-RXN
|
|
|
|
cholesterol + NADP+ <=> desmosterol + NADPH + H+
|
1.3.1.72
Delta24-sterol reductase
|
–
|
MK
|
|
BRENDA:
BS189401
KEGG:
R01457
MetaCyc:
RXN66-28
|
|
|
|
oleoyl-CoA + cholesterol <=> cholesteryl_oleate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320750
MetaCyc:
RXN-20221
SABIO-RK:
14935
|
|
|
|
palmitoyl-CoA + cholesterol <=> cholesteryl_palmitate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320752
MetaCyc:
RXN-20231
|
|
|
|
stearoyl-CoA + cholesterol <=> cholesteryl_stearate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320753
MetaCyc:
RXN-20218
|
|
|
|
linoleoyl-CoA + cholesterol <=> cholesteryl_linoleate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320758
MetaCyc:
RXN-20223
|
|
|
|
3''-phosphoadenylyl-sulfate + cholesterol <=> adenosine_3,5''-bisphosphate + Cholesterol_sulfate + H+
|
2.8.2.14
bile-salt sulfotransferase
2.8.2.15
steroid sulfotransferase
2.8.2.2
alcohol sulfotransferase
|
–
–
–
|
K
|
|
BRENDA:
BS360219;
BS378388;
BS386092
KEGG:
R08977
MetaCyc:
RXN66-602
SABIO-RK:
15393
|
|
|
|
cholesterol + NAD+ <=> 5-Cholesten-3-one + NADH + H+
|
1.1.1.145
3beta-hydroxy-Delta5-steroid dehydrogenase
|
–
|
M
|
|
BRENDA:
BS396694
MetaCyc:
RXN-12693
|
|
|
|
docosahexaenoyl-CoA + cholesterol <=> cholesteryl_docosahexanoate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS409334
MetaCyc:
RXN-20226
|
|
|
|
cholesterol + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> 27-Hydroxycholesterol + oxidized_ferredoxin + H2O
|
1.14.15.29
cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]
|
–
|
|
|
BRENDA:
BS418546
MetaCyc:
RXN-17656
|
|
|
|
cholesterol + reduced_flavodoxin + O2 <=> 7alpha-hydroxycholesterol + flavin + H2O
|
1.14.14.23
cholesterol 7alpha-monooxygenase
|
–
|
BK
|
|
BRENDA:
BR29138
KEGG:
R01463
|
|
|
|
cholesterol + reduced_flavodoxin + O2 <=> (24S)-24-hydroxycholesterol + flavin + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48564
KEGG:
R07207
|
|
|
|
acyl-CoA + cholesterol <=> CoA + cholesteryl_ester
|
2.3.1.26
sterol O-acyltransferase
|
–
|
K
|
|
BRENDA:
BS320749
KEGG:
R01461
|
|
|
|
cholesteryl_ester + H2O <=> cholesterol + fatty_acid
|
3.1.1.13
sterol esterase
|
–
|
K
|
|
BRENDA:
BS363944
KEGG:
R01462
|
|
|
|
Cholesterol_sulfate + H2O <=> cholesterol + sulfate
|
3.1.6.2
steryl-sulfatase
|
–
|
K
|
|
BRENDA:
BS370890
KEGG:
R08941
|
|
|
|
cholesterol + reduced_adrenodoxin + H+ + O2 <=> 27-Hydroxycholesterol + oxidized_ferredoxin + H2O
|
1.14.15.15
cholestanetriol 26-monooxygenase
|
–
|
K
|
|
BRENDA:
BS386397
KEGG:
R08505
|
|
|
|
UDP-glucose + cholesterol <=> UDP + cholesterol_3-beta-D-glucoside
|
2.4.1.173
sterol 3beta-glucosyltransferase
|
–
|
|
|
BRENDA:
BS354595
SABIO-RK:
10334
|
|
|
|
cholesteryl_acetate + H2O <=> cholesterol + acetate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363924
SABIO-RK:
11931
|
|
|
|
cholesteryl_linoleate + H2O <=> cholesterol + linoleic_acid
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363925
SABIO-RK:
11927
|
|
|
|
cholesteryl_stearate + H2O <=> cholesterol + fatty_acid
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363926
SABIO-RK:
11928
|
|
|
|
cholesteryl_myristate + H2O <=> cholesterol + myristic_acid
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363928
SABIO-RK:
11930
|
|
|
|
phosphatidylcholine + cholesterol <=> lysophosphatidylcholine + cholesteryl_ester
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS378721
SABIO-RK:
14076
|
|
|
|
cholesterol + NADPH + O2 <=> (24S)-24-hydroxycholesterol + NADP+ + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
|
–
|
|
|
BRENDA:
BS386394
SABIO-RK:
13204
|
|
|
|
cholesteryl_palmitate + H2O <=> cholesterol + palmitate
|
3.1.1.13
sterol esterase
3.1.1.50
wax-ester hydrolase
|
–
–
|
|
|
BRENDA:
BS73319
SABIO-RK:
11929
|
|
|
|
cholesterol + NAD+ <=> 7-dehydrocholesterol + NADH + H+
|
1.3.1.21
7-dehydrocholesterol reductase
|
–
|
K
|
|
KEGG:
R01451
|
|
|
|
cholesterol + O2 + NADPH + H+ <=> 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + NADP+ + H2O
|
1.14.13
|
–
|
|
|
KEGG:
R01452
|
|
|
|
cholesterol + O2 + NADPH + H+ <=> 5,6beta-epoxy-5beta-cholestan-3beta-ol + NADP+ + H2O
|
1.14.13
|
–
|
|
|
KEGG:
R01453
|
|
|
|
cholesterol + O2 + 2 H+ + 2 reduced_ferredoxin <=> 20alpha-hydroxycholesterol + H2O + 2 oxidized_ferredoxin
|
1.14.15.6
cholesterol monooxygenase (side-chain-cleaving)
|
–
|
K
|
|
KEGG:
R01454
|
|
|
|
diacylglycerol + cholesterol <=> monoacylglycerol + cholesteryl_ester
|
2.3.1.73
diacylglycerol---sterol O-acyltransferase
|
–
|
K
|
|
KEGG:
R02692
|
|
|
|
cholesterol + NAD+ <=> cholest-4-en-3-one + NADH + H+
|
1.1.1.145
3beta-hydroxy-Delta5-steroid dehydrogenase
5.3.3.1
steroid Delta-isomerase
|
–
–
|
K
|
|
KEGG:
R09920
|
|
|
|
cholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (24S)-24-hydroxycholesterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
|
–
|
|
|
MetaCyc:
1.14.13.98-RXN
|
|
|
|
cholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 7alpha-hydroxycholesterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.23
cholesterol 7alpha-monooxygenase
|
–
|
M
|
|
MetaCyc:
CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN
|
|
|
|
UDP-glucose + cholesterol <=> UDP + cholesteryl-beta-D-glucoside + H+
|
2.4.1.173
sterol 3beta-glucosyltransferase
|
–
|
|
|
MetaCyc:
RXN-12127
|
|
|
|
cholesterol + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> (25S)-3beta-hydroxycholest-5-en-26-oate + oxidized_ferredoxin + H2O
|
1.14.15.29
cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]
|
–
|
|
|
MetaCyc:
RXN-12701
|
|
|
|
cholesterol + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> (25S)-26-hydroxycholesterol + H2O + oxidized_ferredoxin
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-17655
|
|
|
|
cholesterol + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> (25R)-3beta-hydroxycholest-5-en-26-oate + oxidized_ferredoxin + H2O
|
1.14.15.28
cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]
|
–
|
|
|
MetaCyc:
RXN-17659
|
|
|
|
UDP-glucose + cholesterol <=> cholesteryl-alpha-D-glucoside + UDP + H+
|
2.4.1
|
–
|
|
|
MetaCyc:
RXN-18283
|
|
|
|
cholesterol + H2O + acceptor <=> 25-hydroxycholesterol + reduced_acceptor
|
1.17.99.e
|
–
|
|
|
MetaCyc:
RXN-19741
|
|
|
|
propionyl-CoA + cholesterol <=> cholesteryl_propionate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20219
|
|
|
|
pentanoyl-CoA + cholesterol <=> cholesteryl_valerate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20220
|
|
|
|
(15Z)-tetracosenoyl-CoA + cholesterol <=> cholesteryl_nervonate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20222
|
|
|
|
hexanoyl-CoA + cholesterol <=> cholesteryl_hexanoate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20224
|
|
|
|
erucoyl-CoA + cholesterol <=> cholesteryl_erucate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20225
|
|
|
|
decanoyl-CoA + cholesterol <=> cholesteryl_decanoate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20227
|
|
|
|
butyryl-CoA + cholesterol <=> cholesteryl_butyrate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20228
|
|
|
|
gamma-linolenoyl-CoA + cholesterol <=> cholesteryl_linolenate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20229
|
|
|
|
(13Z,16Z)-Docosadienoyl-CoA + cholesterol <=> cholest-5-en-3beta-yl_(13Z,16Z-docosadienoate) + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20230
|
|
|
|
Arachidonoyl-CoA + cholesterol <=> cholesteryl_arachidonate + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
RXN-20232
|
|
|
|
cholesterol <=> diosgenin
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-20589
|
|
|
|
cholesterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> (22R)-22-hydroxycholesterol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.13
|
–
|
M
|
|
MetaCyc:
RXN18C3-235
|
|
|
|
stearoyl-CoA + cholesterol <=> long-chain_acyl-cholesterol_ester + CoA
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
MetaCyc:
STEROL-O-ACYLTRANSFERASE-RXN
|
|
|
|
desmosterol + FADH2 <=> cholesterol + FAD + H+
|
1.3.1.72
Delta24-sterol reductase
|
–
|
|
|
BRENDA:
BS396986
|
|
|
|
cholesteryl_decanoate + H2O <=> cholesterol + Decanoate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS416773
|
|
|
|
9,12-octadecadienoyl-CoA + cholesterol <=> CoA + cholesteryl_linelaidate
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320772
|
|
|
|
myristoyl-CoA + cholesterol <=> CoA + cholesteryl_myristate
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320754
|
|
|
|
cholesteryl_butyrate + H2O <=> cholesterol + Butyrate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363932
|
|
|
|
elaidoyl-CoA + cholesterol <=> CoA + cholesteryl_elaidate
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320771
|
|
|
|
lauroyl-CoA + cholesterol <=> CoA + cholesteryl_laurate
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320755
|
|
|
|
cholestanol + ferricytochrome_b5 + H+ + O2 <=> cholesterol + ferricytochrome_b5 + 2 H2O
|
1.14.19.20
Delta7-sterol 5(6)-desaturase
|
–
|
|
|
BRENDA:
BS402385
|
|
|
|
cholesteryl_hexanoate + H2O <=> cholesterol + hexanoate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS416774
|
|
|
|
palmitoleoyl-CoA + cholesterol <=> CoA + cholesteryl_palmitoleate
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320751
|
|
|
|
cholesterol + reduced_flavodoxin + O2 <=> 12-hydroxycholesterol + flavin + H2O
|
1.14.14.139
5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase
|
–
|
|
|
BRENDA:
BS386395
|
|
|
|
cholesterol + 1-palmitoyl-2-docosahexaenoyl-phosphatidylcholine <=> cholesteryl_docosahexanoate + 1-palmitoyl-sn-glycero-3-phosphocholine
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320909
|
|
|
|
cholesterol + 1-palmitoyl-2-arachidonoylphosphatidylcholine <=> cholesteryl_arachidonate + 1-palmitoyl-sn-glycero-3-phosphocholine
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320907
|
|
|
|
cholesterol + 1-palmitoyl-2-linoleoylphosphatidylcholine <=> cholesteryl_linoleate + 1-palmitoyl-sn-glycero-3-phosphocholine
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320906
|
|
|
|
cholesterol + 1-palmitoyl-2-(5Z,8Z,11Z,14Z,17Z)-eicosapenta-5,8,11,14,17-enoylphosphatidylcholine <=> (3beta)-cholest-5-en-3-yl_(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate + 1-palmitoyl-sn-glycero-3-phosphocholine
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320908
|
|
|
|
cholesterol + 1-palmitoyl-2-phytanoylphosphatidylcholine <=> cholesteryl_phytanoate + 1-palmitoyl-sn-glycero-3-phosphocholine
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320911
|
|
|
|
cholesterol + 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine <=> cholesteryl_oleate + 1-palmitoyl-sn-glycero-3-phosphocholine
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320905
|
|
|
|
cholesterol + 1-O-hexadecyl-2-oleylphosphatidylcholine <=> cholesteryl_oleate + 1-palmitoyl-sn-glycero-3-phosphocholine
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320910
|
|
|
|
cholesterol + O2 <=> 6beta-hydroperoxycholest-4-en-3-one + H2O2
|
1.1.3.6
cholesterol oxidase
|
–
|
|
|
BRENDA:
BS188883
|
|
|
|
cholesterol + O2 <=> 6beta-hydroxycholest-5-en-3-one + H2O2
|
1.1.3.6
cholesterol oxidase
|
–
|
|
|
BRENDA:
BS440192
|
|
|
|
cholesteryl_laurate + H2O <=> cholesterol + laurate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363929
|
|
|
|
cholesterol + diacylglycerol <=> monoacylglycerol + cholesterol-3-O-acyl_ester
|
2.3.1.73
diacylglycerol---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS321277
|
|
|
|
cholesterol + reduced_adrenodoxin + O2 <=> 25-hydroxycholesterol + oxidized_ferredoxin + H2O
|
1.14.15.15
cholestanetriol 26-monooxygenase
|
–
|
|
|
BRENDA:
BS388315
|
|
|
|
acetyl-CoA + cholesterol <=> CoA + cholesteryl_acetate
|
2.3.1.26
sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320756
|
|
|
|
cholesteryl_arachidonate + H2O <=> cholesterol + arachidonic_acid
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS92867
|
|
|
|
cholesteryl_caprylate + H2O <=> cholesterol + Octanoate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363927
|
|
|
|
cholesteryl_elaidate + H2O <=> cholesterol + elaidic_acid
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363941
|
|
|
|
Trilinolein + cholesterol <=> dilinoleoylglycerol + cholesteryl_linoleate
|
2.3.1.77
triacylglycerol---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS321320
|
|
|
|
cholesterol + 1-phytanoyl-2-palmitoylphosphatidylcholine <=> cholesteryl_palmitate + 1-phytanylglyerophosphocholine
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320912
|
|
|
|
Tripalmitoylglycerol + cholesterol <=> 1,2-dipalmitoyl-sn-glycerol + cholesteryl_palmitate
|
2.3.1.77
triacylglycerol---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS321316
|
|
|
|
cholesterol_3-sulfate + H2O <=> cholesterol + sulfate
|
3.1.6.2
steryl-sulfatase
|
–
|
|
|
BRENDA:
BS93850
|
|
|
|
cholesterol + 6 reduced_adrenodoxin_mutant_S112W + 3 O2 <=> pregnenolone + 4-Methylpentanal + 6 oxidized_adrenodoxin_mutant_S112W + 4 H2O
|
1.14.15.6
cholesterol monooxygenase (side-chain-cleaving)
|
–
|
|
|
BRENDA:
BS426100
|
|
|
|
cholesterol + reduced_ferredoxin + O2 <=> pregnenolone + adrenal_ferredoxin + H2O
|
1.14.15.6
cholesterol monooxygenase (side-chain-cleaving)
|
–
|
|
|
BRENDA:
BS394800
|
|
|
|
tristearin + cholesterol <=> 1,2-distearoylglycerol + cholesteryl_stearate
|
2.3.1.77
triacylglycerol---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS321321
|
|
|
|
cholesterol + reduced_adrenodoxin + O2 <=> (24S)-24-hydroxycholesterol + oxidized_ferredoxin + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
1.14.15.15
cholestanetriol 26-monooxygenase
|
–
–
|
|
|
BRENDA:
BS386396
|
|
|
|
phosphatidylethanolamine + cholesterol <=> cholesteryl_ester + lysophosphatidylethanolamine
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS410088
|
|
|
|
triacylglycerol + cholesterol <=> Diacylglycerols + cholesteryl_ester
|
2.3.1.77
triacylglycerol---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS321317
|
|
|
|
cholesteryl_ester + H2O <=> cholesterol + a_carboxylate
|
3.1.1.79
hormone-sensitive lipase
|
–
|
|
|
BRENDA:
BS370891
|
|
|
|
L-alpha-phosphatidylcholine_type_XVI-E + cholesterol <=> lysophosphatidylcholine + cholesteryl_ester
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS455810
|
|
|
|
1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine + cholesterol <=> cholesteryl-1-pyrenebutyrate + lysophosphatidylcholine
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS320916
|
|
|
|
cholesterol + NADPH + H+ + O2 <=> 22-hydroxycholesterol + NADP+ + H2O
|
1.14.99.B1
|
–
|
|
|
BRENDA:
BS396696
|
|
|
|
cholesterol + O2 + NADH + H+ <=> 7-dehydrocholesterol + NADP+ + H2O
|
1.14.19.21
cholesterol 7-desaturase
|
–
|
|
|
BRENDA:
BS432743
|
|
|
|
cholesteryl_erucate + H2O <=> cholesterol + erucic_acid
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS92868
|
|
|
|
cholesteryl_nervonate + H2O <=> cholesterol + nervonic_acid
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS92869
|
|
|
|
Cholesteryl_eicosenoate + H2O <=> cholesterol + 11-eicosenoic_acid
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS92866
|
|
|
|
cholesteryl_valerate + H2O <=> cholesterol + pentanoate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS92876
|
|
|
|
cholesteryl_caprate + H2O <=> cholesterol + Decanoate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363930
|
|
|
|
cholesteryl_caproate + H2O <=> cholesterol + hexanoate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363931
|
|
|
|
cholesteryl_propionate + H2O <=> cholesterol + propionate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS363943
|
|
|
|
ATP + H2O + cholesterol <=> ADP + phosphate + cholesterol
|
7.6.2.2
ABC-type xenobiotic transporter
|
–
|
|
|
BRENDA:
BS444220
|
|
|
|
ATP + H2O + cholesterol/in <=> ADP + phosphate + cholesterol
|
7.6.2.2
ABC-type xenobiotic transporter
|
–
|
|
|
BRENDA:
BS190146
|
|
|
|
cholesterol_acetate + H2O <=> cholesterol + acetate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS381657
|
|
|
|
cholesterol_butyrate + H2O <=> cholesterol + Butyrate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS381658
|
|
|
|
cholesterol_decanoate + H2O <=> cholesterol + Decanoate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS381659
|
|
|
|
cholesterol_hexanoate + H2O <=> cholesterol + hexanoate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS381660
|
|
|
|
cholesterol_linoleate + H2O <=> cholesterol + linoleic_acid
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS381661
|
|
|
|
cholesterol_palmitate + H2O <=> cholesterol + palmitate
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS381662
|
|
|
|
cholesteryl_linolenate + H2O <=> cholesterol + linolenic_acid
|
3.1.1.13
sterol esterase
|
–
|
|
|
BRENDA:
BS381663
|
|
|
|
triolein + cholesterol <=> 1,2-dioleoylglycerol + cholesteryl_oleate
|
2.3.1.77
triacylglycerol---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS321319
|
|
|
|
dioleoyl-phosphatidylcholine + cholesterol <=> 1-oleoyl-sn-glycero-3-phosphocholine + cholesteryl_oleate
|
2.3.1.43
phosphatidylcholine---sterol O-acyltransferase
|
–
|
|
|
BRENDA:
BS388583
|
|
|
|
cholesteryl_oleate + H2O <=> cholesterol + oleic_acid
|
3.1.1.1
carboxylesterase
3.1.1.13
sterol esterase
3.1.1.3
triacylglycerol lipase
3.1.1.67
fatty-acyl-ethyl-ester synthase
3.1.1.79
hormone-sensitive lipase
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
|
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS115427
|
|
|
|
cholesterol + 6 [2Fe-2S]-center + 3 O2 <=> 5-cholestene-26-oic_acid-3beta-ol + 6 [2Fe-2S]-center + 4 H2O
|
1.14.15.28
cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]
|
–
|
|
|
BRENDA:
BS435397
|
|
|
|
cholesterol + 6 [2Fe-2S]-center + 3 O2 <=> (25S)-3beta-hydroxycholest-5-en-26-oate + 6 [2Fe-2S]-center + 4 H2O
|
1.14.15.29
cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]
|
–
|
|
|
BRENDA:
BS442355
|
|
|
|
cholesterol + 6 [2Fe-2S]-center + 3 O2 <=> (25R)-3beta-hydroxycholest-5-en-26-oate + 6 [2Fe-2S]-center + 4 H2O
|
1.14.15.28
cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]
|
–
|
|
|
BRENDA:
BS443288
|
|
|
|
O2 + NADPH + H+ + cholesterol <=> H2O + 7alpha-hydroxycholesterol + NADP+
|
1.14.14.23
cholesterol 7alpha-monooxygenase
|
–
|
|
|
SABIO-RK:
1640
|
|
|
|
cholesterol + NADP+ <=> H+ + 5-Cholesten-3-one + NADPH
|
1.1.1.146
11beta-hydroxysteroid dehydrogenase
|
–
|
|
|
SABIO-RK:
13527
|
|